Feed-grade nano-zinc oxide has extremely high bioactivity and absorptivity. With extremely high oxidability as well as sterilization and detoxication capacity, it can effectively reduce diarrhea and feed conversion ratio, is pollution-free to the environment, and is the most ideal feed additive for replacing high zinc at present. With the research and development of nanometer technologies, increasingly advanced processing and manufacturing technologies as well as mass production, its manufacturing cost is also reduced increasingly, thus its application cost in feed will also be gradually reduced. Microelement nanometer treatment is a revolution in microelement nutrition, which has good growth promotion effect, low addition amount and reduced feed cost, what’s more, reduces environmental pollution, benefiting human health. Therefore, nano-zinc oxide has an extremely wide application prospect in the feed industry.